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914805-33-7

914805-33-7 structure
914805-33-7 structure
  • Name: Shield-1
  • Chemical Name: Shield-1
  • CAS Number: 914805-33-7
  • Molecular Formula: C42H56N2O10
  • Molecular Weight: 748.90
  • Catalog: Research Areas Others
  • Create Date: 2019-10-08 14:51:52
  • Modify Date: 2025-08-25 11:25:08
  • Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein[1][2].

Name Shield-1
Description Shield-1 is a specific, cell-permeant and high-affinity ligand of FK506-binding protein-12 (FKBP), and reverses the instability by binding to mutated FKBP (mtFKBP), allowing conditional expression of mtFKBP-fused proteins. Shield-1 can stabilize the entire fusion protein[1][2].
Related Catalog
References

[1]. Schoeber JP, et al. Conditional fast expression and function of multimeric TRPV5 channels using Shield-1. Am J Physiol Renal Physiol. 2009 Jan;296(1):F204-11.

[2]. Li S, et al. Effects of Shield1 on the viral replication of varicella zoster virus containing FKBP tagged ORF4and 48. Mol Med Rep. 2018 Jan;17(1):763-770.

Molecular Formula C42H56N2O10
Molecular Weight 748.90
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