topramezone
Modify Date: 2024-01-02 21:18:51
topramezone structure
|
Common Name | topramezone | ||
|---|---|---|---|---|
| CAS Number | 210631-68-8 | Molecular Weight | 363.388 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 590.5±60.0 °C at 760 mmHg | |
| Molecular Formula | C16H17N3O5S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 310.9±32.9 °C | |
| Symbol |
GHS08, GHS09 |
Signal Word | Danger | |
Use of topramezoneTopramezone is a potent 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor. Topramezone is a herbicide, used for the post-emergence control of broadleaf and grass weeds in corn[1]. |
| Name | topramezone |
|---|---|
| Synonym | More Synonyms |
| Description | Topramezone is a potent 4-hydroxyphenylpyruvate dioxygenase (4-HPPD) inhibitor. Topramezone is a herbicide, used for the post-emergence control of broadleaf and grass weeds in corn[1]. |
|---|---|
| In Vitro | Topramezone (5, 10, 20, 30, 45 mg/L; 24-96 h) inhibits algal (C. vulgaris) growth by triggering oxidative stress, damaging cell morphology and photosynthetic activity during the exposure[1]. Topramezone (20 mg/L; 24, 48, 72 and 96 h) disrupts the photosynthetic system, by decreasing the content of photosynthetic pigments, and induces ROS (oxidative stress) with an increase of MDA in a time-dependent manner[1]. Topramezone (20 mg/L; 96 h) compromises the integrity of the cells, damages chloroplasts and membranes in algal cells and triggers apoptosis[1]. Topramezone (0.1 nM-0.1 mM; 30 min) exhibits selectivity and inhibits 4-HPPD (recombinant enzyme protein) activity in vitro, with IC50s of 15 nM (Setaria faberi), 23 nM (Arabidopsis thaliana), and 180 nM (Corn)[2]. topramezone (foliar-applied; containing [14C]topramezone of 0.29 µg; 24 and 48 h) is metabolized faster in corn than in the weeds[2]. |
| References |
| Density | 1.5±0.1 g/cm3 |
|---|---|
| Boiling Point | 590.5±60.0 °C at 760 mmHg |
| Molecular Formula | C16H17N3O5S |
| Molecular Weight | 363.388 |
| Flash Point | 310.9±32.9 °C |
| Exact Mass | 363.088898 |
| PSA | 119.23000 |
| LogP | 0.96 |
| Vapour Pressure | 0.0±1.7 mmHg at 25°C |
| Index of Refraction | 1.670 |
| Symbol |
GHS08, GHS09 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H360-H410 |
| Precautionary Statements | P201-P273-P308 + P313-P501 |
| Personal Protective Equipment | Eyeshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges |
| Hazard Codes | T,N |
| Risk Phrases | 61-50/53 |
| Safety Phrases | 53-45-60-61 |
| RIDADR | UN3077 9/PG 3 |
| 4-[2-methyl-3-(4,5-dihydroisoxazol-3-yl)-4-methylsulfonylbenzoyl ]-1-methyl-5-hydroxy-1H-pyrazole |
| 4-[3-(4,5-dihydroisoxazol-3-yl)-4-methylsulfonyl-2-methylbenzoyl]-5-hydroxy-1-methylpyrazole |
| 4-[3-(4,5-dihydro-1,2-oxazol-3-yl)-2-methyl-4-methylsulfonylbenzoyl]-2-methyl-1H-pyrazol-3-one |
| Methanone, [3-(4,5-dihydro-3-isoxazolyl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)- |
| [3-(4,5-Dihydroisoxazol-3-yl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)methanone |
| 11322047 |
| T5NO EUTJ ER B1 FSW1 CV- DTNNJ A1 EQ |
| 1-methyl-4-(3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-methyl-sulfonylbenzoyl)-5-hydroxypyrazole |
| [3-(4,5-dihydro-3-isoxazolyl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)methanone |
| [3-(4,5-dihydro-1,2-oxazol-3-yl)-4-(methanesulfonyl)-2-methylphenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)methanone |
| benzuocaotong |
| [3-(4,5-Dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)methanone |
| 4-[3-(4,5-dihydroisoxazol-3-yl)-2-methyl-4-methylsulfonyl-benzoyl]-1-methyl-5-hydroxy-1H-pyrazole |
| topramezone |
| [3-(4,5-dihydro-1,2-oxazol-3-yl)-4-mesyl-o-tolyl](5-hydroxy-1-methyl-1H-pyrazole-4-yl)methanone |
| [3-(4,5-dihydro-1,2-oxazol-3-yl)-4-mesyl-o-tolyl](5-hydroxy-1-methylpyrazol-4-yl)methanone |
| [3-(4,5-Dihydro-1,2-oxazol-3-yl)-2-methyl-4-(methylsulfonyl)phenyl](5-hydroxy-1-methyl-1H-pyrazol-4-yl)methanon |