IPN60090 dihydrochloride structure
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Common Name | IPN60090 dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 2102101-72-2 | Molecular Weight | 605.44 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C24H29Cl2F3N8O3 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of IPN60090 dihydrochlorideIPN-60090 dihydrochloride is an orally bioavailable and selective inhibitor of GLS1 (the kidney-type glutaminase), an important enzyme for metabolic energy production. IPN-60090 dihydrochloride can be used in the research of GLS1-mediated diseases[1][2]. |
| Name | IPN-60090 dihydrochloride |
|---|
| Description | IPN-60090 dihydrochloride is an orally bioavailable and selective inhibitor of GLS1 (the kidney-type glutaminase), an important enzyme for metabolic energy production. IPN-60090 dihydrochloride can be used in the research of GLS1-mediated diseases[1][2]. |
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| Related Catalog | |
| Target |
GLS1[1] |
| In Vitro | IPN-60090 dihydrochloride (Example 1) has an IC50 against GLS1 and an EC50 against A549 cell proliferation of <100 nM[2]. |
| References |
[1]. Maria Emilia Di Francesco, et al. Gls1 inhibitors for treating disease. WO2016004404A2. |
| Molecular Formula | C24H29Cl2F3N8O3 |
|---|---|
| Molecular Weight | 605.44 |