PI3Kδ-IN-8
Modify Date: 2025-08-27 18:54:26
PI3Kδ-IN-8 structure
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Common Name | PI3Kδ-IN-8 | ||
|---|---|---|---|---|
| CAS Number | 2101518-75-4 | Molecular Weight | 509.51 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C28H21F2N7O | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of PI3Kδ-IN-8PI3Kδ-IN-8 is a potent, selective and orally active PI3Kδ, with an IC50 of 3.3 nM. PI3Kδ-IN-8 shows selectivity for PI3Kδ over PI3Kα, PI3Kβ, and PI3Kγ (IC50=377.2, 241.6, 17.9 nM, respectively). PI3Kδ-IN-8 has anti-tumor activity. |
| Name | PI3Kδ-IN-8 |
|---|
| Description | PI3Kδ-IN-8 is a potent, selective and orally active PI3Kδ, with an IC50 of 3.3 nM. PI3Kδ-IN-8 shows selectivity for PI3Kδ over PI3Kα, PI3Kβ, and PI3Kγ (IC50=377.2, 241.6, 17.9 nM, respectively). PI3Kδ-IN-8 has anti-tumor activity. |
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| Molecular Formula | C28H21F2N7O |
|---|---|
| Molecular Weight | 509.51 |
| InChIKey | YPUUKLQYBLWUEU-HNNXBMFYSA-N |
| SMILES | CC(Nc1nc(N)nc(N)c1C#N)c1c(-c2ccccc2)c(=O)n2cc(F)ccc2c1-c1ccc(F)cc1 |