1-Methylindole-6-carbaldehyde

Modify Date: 2024-01-02 16:30:44

1-Methylindole-6-carbaldehyde Structure
1-Methylindole-6-carbaldehyde structure
Common Name 1-Methylindole-6-carbaldehyde
CAS Number 21005-45-8 Molecular Weight 159.18500
Density 1.1g/cm3 Boiling Point 318.7ºC at 760mmHg
Molecular Formula C10H9NO Melting Point 81ºC
MSDS Chinese USA Flash Point 146.5ºC
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 1-Methylindole-6-carbaldehyde
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.1g/cm3
Boiling Point 318.7ºC at 760mmHg
Melting Point 81ºC
Molecular Formula C10H9NO
Molecular Weight 159.18500
Flash Point 146.5ºC
Exact Mass 159.06800
PSA 22.00000
LogP 1.99080
Vapour Pressure 0.000356mmHg at 25°C
Index of Refraction 1.585

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H319-H412
Precautionary Statements P273-P305 + P351 + P338
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

~78%

1-Methylindole-6-carbaldehyde Structure

1-Methylindole-...

CAS#:21005-45-8

Literature: Wang, Guangcheng; Li, Chunyan; He, Lin; Lei, Kai; Wang, Fang; Pu, Yuzi; Yang, Zhuang; Cao, Dong; Ma, Liang; Chen, Jinying; Sang, Yun; Liang, Xiaolin; Xiang, Mingli; Peng, Aihua; Wei, Yuquan; Chen, Lijuan Bioorganic and Medicinal Chemistry, 2014 , vol. 22, # 7 p. 2060 - 2079

~24%

1-Methylindole-6-carbaldehyde Structure

1-Methylindole-...

CAS#:21005-45-8

Literature: AFFINIUM PHARMACEUTICALS, INC. Patent: WO2007/53131 A2, 2007 ; Location in patent: Page/Page column 157 ; WO 2007/053131 A2

~%

1-Methylindole-6-carbaldehyde Structure

1-Methylindole-...

CAS#:21005-45-8

Literature: US5891901 A1, ;

~%

1-Methylindole-6-carbaldehyde Structure

1-Methylindole-...

CAS#:21005-45-8

Literature: Journal of Organometallic Chemistry, , vol. 696, # 5 p. 1072 - 1083

~%

1-Methylindole-6-carbaldehyde Structure

1-Methylindole-...

CAS#:21005-45-8

Literature: Chemical and Pharmaceutical Bulletin, , vol. 34, # 10 p. 4109 - 4115

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles1

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Rational design of novel CYP2A6 inhibitors.

Bioorg. Med. Chem. 22(23) , 6655-64, (2015)

Inhibition of CYP2A6-mediated nicotine metabolism can reduce cigarette smoking. We sought potent and selective CYP2A6 inhibitors to be used as leads for drugs useful in smoking reduction therapy, by e...

 Synonyms

1-Methyl-1H-indole-6-carbaldehyde
1-methyl-1H-indole-6-carbaldehyde
6-formyl-1-methylindole
N-methyl-6-indolecarboxaldehyde
1-methyl-indole-6-carboxaldehyde
1-methyl-6-indolecarbaldehyde
1-Methyl-1H-indole-6-carboxaldehyde
1-methyl-1H-indole-6-carboxaldehyde