Ontamalimab

Modify Date: 2024-09-18 08:42:11

Ontamalimab Structure
Ontamalimab structure
Common Name Ontamalimab
CAS Number 2098790-40-8 Molecular Weight N/A
Density N/A Boiling Point N/A
Molecular Formula N/A Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ontamalimab


Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Ontamalimab can be used for the research of Crohn's disease[1].

 Names

Name Ontamalimab

 Ontamalimab Biological Activity

Description Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Ontamalimab can be used for the research of Crohn's disease[1].
Related Catalog
Target

mucosal addressin cell adhesion molecule-1 (MAdCAM-1)[1]

In Vitro Ontamalimab 以高亲和力选择性结合 MAdCAM-1,诱导特定白细胞亚群的运输[1]。
References

[1]. D'Haens GR, et, al. Long-Term Safety and Efficacy of the Anti-Mucosal Addressin Cell Adhesion Molecule-1 Monoclonal Antibody Ontamalimab (SHP647) for the Treatment of Crohn's Disease: The OPERA II Study. Inflamm Bowel Dis. 2022 Jul 1;28(7):1034-1044.  

 Chemical & Physical Properties

No Any Chemical & Physical Properties
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