Ontamalimab

Names

[ CAS No. ]:
2098790-40-8

[ Name ]:
Ontamalimab

Biological Activity

[Description]:

Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1). Ontamalimab can be used for the research of Crohn's disease[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[Target]

mucosal addressin cell adhesion molecule-1 (MAdCAM-1)[1]

[In Vitro]

Ontamalimab 以高亲和力选择性结合 MAdCAM-1，诱导特定白细胞亚群的运输[1]。

[References]

[1]. D'Haens GR, et, al. Long-Term Safety and Efficacy of the Anti-Mucosal Addressin Cell Adhesion Molecule-1 Monoclonal Antibody Ontamalimab (SHP647) for the Treatment of Crohn's Disease: The OPERA II Study. Inflamm Bowel Dis. 2022 Jul 1;28(7):1034-1044.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Related Compounds

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