DPPY

Modify Date: 2023-01-11 16:44:30

DPPY structure	Common Name	DPPY
	CAS Number	2095883-62-6	Molecular Weight	507.97
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₅H₂₆ClN₇O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of DPPY

DPPY (compound 6) is a potent PTK inhibitor with IC50 values of <10, <10, <10 nM for EGFR, BTK, JAK3, respectively. DPPY shows anti-proliferative activity against B-cell lymphoma cells. DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF)[1].

Name	DPPY

Description	DPPY (compound 6) is a potent PTK inhibitor with IC50 values of <10, <10, <10 nM for EGFR, BTK, JAK3, respectively. DPPY shows anti-proliferative activity against B-cell lymphoma cells. DPPY has the potential for the research of idiopathic pulmonary fibrosis (IPF)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> EGFR Signaling Pathways >> JAK/STAT Signaling >> JAK Signaling Pathways >> Epigenetics >> JAK Signaling Pathways >> Stem Cell/Wnt >> JAK Signaling Pathways >> Protein Tyrosine Kinase/RTK >> EGFR Research Areas >> Inflammation/Immunology Signaling Pathways >> Protein Tyrosine Kinase/RTK >> Btk
Target	JAK3:<10 nM (IC50) EGFR:<10 nM (IC50) BTK:<10 nM (IC50)
References	[1]. Zhu Y, et al. Synthesis and biological activity of thieno[3,2-d]pyrimidines as potent JAK3 inhibitors for the treatment of idiopathic pulmonary fibrosis. Bioorg Med Chem. 2020 Jan 15;28(2):115254.

Molecular Formula	C₂₅H₂₆ClN₇O₃
Molecular Weight	507.97

DPPY

Use of DPPY

Names

DPPY Biological Activity

Chemical & Physical Properties