YQ456

Modify Date: 2025-09-08 20:53:00

YQ456 Structure
YQ456 structure
Common Name YQ456
CAS Number 2093946-08-6 Molecular Weight 454.56
Density N/A Boiling Point N/A
Molecular Formula C28H30N4O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of YQ456


YQ456 is a novel small molecule inhibitor of myoferlin that showed high binding affinity to myoferlin with a KD of 37 nM and excellent anti-invasion capability with an IC50 of 110 nM.

 Names

Name YQ456

 YQ456 Biological Activity

Description YQ456 is a novel small molecule inhibitor of myoferlin that showed high binding affinity to myoferlin with a KD of 37 nM and excellent anti-invasion capability with an IC50 of 110 nM.
Related Catalog
Target

MYOF:110 nM (IC50)

References

[1]. He Y, et al. A potent and selective small molecule inhibitor of myoferlin attenuates colorectal cancer progression. Clin Transl Med. 2021 Feb;11(2):e289.

 Chemical & Physical Properties

Molecular Formula C28H30N4O2
Molecular Weight 454.56
InChIKey MSZAOWHKERXHJX-UHFFFAOYSA-N
SMILES CCc1nc(-c2ccc(OC)cc2)n(-c2cccc(C(=O)NCCCCc3ccccc3)c2)n1
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