YQ456

Names

[ CAS No. ]:
2093946-08-6

[ Name ]:
YQ456

Biological Activity

[Description]:

YQ456 is a novel small molecule inhibitor of myoferlin that showed high binding affinity to myoferlin with a KD of 37 nM and excellent anti-invasion capability with an IC50 of 110 nM.

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[Target]

MYOF:110 nM (IC50)

[References]

[1]. He Y, et al. A potent and selective small molecule inhibitor of myoferlin attenuates colorectal cancer progression. Clin Transl Med. 2021 Feb;11(2):e289.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₈H₃₀N₄O₂

[ Molecular Weight ]:
454.56

Related Compounds

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