Finafloxacin

Modify Date: 2024-01-04 19:12:15

Finafloxacin structure	Common Name	Finafloxacin
	CAS Number	209342-40-5	Molecular Weight	398.388
	Density	1.6±0.1 g/cm3	Boiling Point	686.2±55.0 °C at 760 mmHg
	Molecular Formula	C₂₀H₁₉FN₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	368.8±31.5 °C

Use of Finafloxacin

Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. Target: AntibacterialFinafloxacin is a pH-activated fluoroquinolone (belonging to a new 8-cyano subclass) to treat serious bacterial infections associated with an acidic environment, including urinary tract infections (UTIs) and Helicobacter pylori infections. Finafloxacin exhibits optimal efficacy in slightly acidic environments (pH 5.0-6.0), under which other fluoroquinolones lose activity. Finafloxacin is highly selective for bacterial type II topoisomerases, including DNA gyrase and DNA topoisomerase IV. [1]

Name	finafloxacin
Synonym	More Synonyms

Description	Finafloxacin is a fluoroquinolone antimicrobial agent that exhibits optimum efficacy in slightly acidic environments. Target: AntibacterialFinafloxacin is a pH-activated fluoroquinolone (belonging to a new 8-cyano subclass) to treat serious bacterial infections associated with an acidic environment, including urinary tract infections (UTIs) and Helicobacter pylori infections. Finafloxacin exhibits optimal efficacy in slightly acidic environments (pH 5.0-6.0), under which other fluoroquinolones lose activity. Finafloxacin is highly selective for bacterial type II topoisomerases, including DNA gyrase and DNA topoisomerase IV. [1]
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection
References	[1]. McKeage K. Finafloxacin: first global approval. Drugs. 2015 Apr;75(6):687-93.

Density	1.6±0.1 g/cm3
Boiling Point	686.2±55.0 °C at 760 mmHg
Molecular Formula	C₂₀H₁₉FN₄O₄
Molecular Weight	398.388
Flash Point	368.8±31.5 °C
Exact Mass	398.139038
PSA	107.59000
LogP	-0.85
Vapour Pressure	0.0±2.2 mmHg at 25°C
Index of Refraction	1.700
Storage condition	2-8℃

Finafloxacin

(-)-8-Cyano-1-cyclopropyl-6-fluoro-7-((4aS,7aS)-hexahydropyrrolo(3,4-b)-1,4-oxazin-6(2H)-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

8-cyano-1-cyclopropyl-6-fluoro-7-((1S,6S)-2-oxa-5,8-diazabicyclo[4.3.0]non-8-yl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

QCR-30

3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-

UNII-D26OSN9Q4R

8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid

Finafloxacin [INN]

7-[(4aS,7aS)-3,4,4a,5,7,7a-hexahydro-2H-pyrrolo[3,4-b][1,4]oxazin-6-yl]-8-cyano-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid

Xtoro

8-Cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b][1,4]oxazin-6(2H)-yl]-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid

DC Chemicals Limited
China
Product Name: Finafloxacin (BAY35-3377)
Price: $500.0/10mg $900.0/25mg $1800.0/100mg
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 3-Quinolinecarboxylic acid, 8-cyano-1-cyclopropyl-6-fluoro-7-[(4aS,7aS)-hexahydropyrrolo[3,4-b]-1,4-oxazin-6(2H)-yl]-1,4-dihydro-4-oxo-
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Stocking Period: Inquiry
Contact: Ms Wang

Get all suppliers and price by the below link:

Finafloxacin suppliers

Price: $368/10mM*1mLinDMSO

Reference only. check more Finafloxacin price

Finafloxacin

Use of Finafloxacin

Names

Finafloxacin Biological Activity

Chemical & Physical Properties

Synonyms