Thalidomide-NH-CH2-COO(t-Bu)

Modify Date: 2024-08-13 09:28:33

Thalidomide-NH-CH2-COO(t-Bu) Structure
Thalidomide-NH-CH2-COO(t-Bu) structure
Common Name Thalidomide-NH-CH2-COO(t-Bu)
CAS Number 2093386-23-1 Molecular Weight 387.39
Density N/A Boiling Point N/A
Molecular Formula C19H21N3O6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Thalidomide-NH-CH2-COO(t-Bu)


Thalidomide-NH-CH2-COO (t-Bu) is a molecular block of small-molecule degrader[1].

 Names

Name Glycine, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-, 1,1-dimethylethyl ester

 Thalidomide-NH-CH2-COO(t-Bu) Biological Activity

Description Thalidomide-NH-CH2-COO (t-Bu) is a molecular block of small-molecule degrader[1].
Related Catalog
References

[1]. Zhou B, et al. Discovery of a Small-Molecule Degrader of Bromodomain and Extra-Terminal (BET) Proteins with Picomolar Cellular Potencies and Capable of Achieving Tumor Regression. J Med Chem. 2018 Jan 25;61(2):462-481.  

 Chemical & Physical Properties

Molecular Formula C19H21N3O6
Molecular Weight 387.39
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