N-(Propargyl-PEG4)-N-bis(PEG4-acid) HCl

Modify Date: 2024-01-10 18:44:19

N-(Propargyl-PEG4)-N-bis(PEG4-acid) HCl Structure
N-(Propargyl-PEG4)-N-bis(PEG4-acid) HCl structure
Common Name N-(Propargyl-PEG4)-N-bis(PEG4-acid) HCl
CAS Number 2093153-09-2 Molecular Weight 727.83
Density N/A Boiling Point N/A
Molecular Formula C33H61NO16 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of N-(Propargyl-PEG4)-N-bis(PEG4-acid) HCl


N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N-(Propargyl-PEG4)-N-bis(PEG4-acid)
Synonym More Synonyms

 N-(Propargyl-PEG4)-N-bis(PEG4-acid) HCl Biological Activity

Description N-(Propargyl-PEG4)-N-bis(PEG4-acid) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C33H61NO16
Molecular Weight 727.83

 Synonyms

MFCD30723276
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