(R)-ZINC 3573
Modify Date: 2025-09-19 14:36:16
(R)-ZINC 3573 structure
|
Common Name | (R)-ZINC 3573 | ||
|---|---|---|---|---|
| CAS Number | 2089389-15-9 | Molecular Weight | 307.393 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C18H21N5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of (R)-ZINC 3573(R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases; activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release. |
| Name | (R)-ZINC-3573 |
|---|---|
| Synonym | More Synonyms |
| Description | (R)-ZINC-3573 is a potent, selective agonist of the atypical opioid receptor MRGPRX2 (EC50=0.76 uM), showing little activity against 315 other GPCRs and 97 representative kinases; activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release. |
|---|---|
| References | References 1. Lansu K, et al. Nat Chem Biol. 2017 May;13(5):529-536. View Related Products by Target Other Targets |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Molecular Formula | C18H21N5 |
| Molecular Weight | 307.393 |
| Exact Mass | 307.179688 |
| LogP | 1.36 |
| Index of Refraction | 1.671 |
| InChIKey | XKBSPAZCFAIBJL-UHFFFAOYSA-N |
| SMILES | CN(C)C1CCN(c2cc(-c3ccccc3)nc3ccnn23)C1 |
| Storage condition | 2-8°C |
| (R)-ZINC-3573 |
| 3-Pyrrolidinamine, N,N-dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-, (3R)- |
| (3R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine |
| (R)-ZINC72453573 |
| (R)-N,N-Dimethyl-1-(5-phenylpyrazolo[1,5-a]pyrimidin-7-yl)-3-pyrrolidinamine |