3’-F-3’-dG(iBu)-2’-phosphoramidite

Modify Date: 2025-09-27 20:05:07

3’-F-3’-dG(iBu)-2’-phosphoramidite structure	Common Name	3’-F-3’-dG(iBu)-2’-phosphoramidite
	CAS Number	2080404-21-1	Molecular Weight	857.91
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄₄H₅₃FN₇O₈P	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 3’-F-3’-dG(iBu)-2’-phosphoramidite

3’-F-3’-dG(iBu)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	3’-F-3’-dG(iBu)-2’-phosphoramidite

Description	3’-F-3’-dG(iBu)-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₄₄H₅₃FN₇O₈P
Molecular Weight	857.91
InChIKey	VRYMRGCKBRUVPH-UHFFFAOYSA-N
SMILES	COc1ccc(C(OCC2OC(n3cnc4c(=O)[nH]c(NC(=O)C(C)C)nc43)C(OP(OCCC#N)N(C(C)C)C(C)C)C2F)(c2ccccc2)c2ccc(OC)cc2)cc1

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3’-F-3’-dG(iBu)-2’-phosphoramidite

Use of 3’-F-3’-dG(iBu)-2’-phosphoramidite

Names

3’-F-3’-dG(iBu)-2’-phosphoramidite Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.