BLT2 antagonist-1

Modify Date: 2024-01-09 16:12:12

BLT2 antagonist-1 Structure
BLT2 antagonist-1 structure
Common Name BLT2 antagonist-1
CAS Number 2069220-61-5 Molecular Weight 435.49
Density N/A Boiling Point N/A
Molecular Formula C26H26FNO4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of BLT2 antagonist-1


BLT2 antagonist-1 (compound 15b) is a selective BLT2 antagonist that inhibits the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM. BLT2 antagonist-1 does not inhibits the chemotaxis of CHO-BLT1 cells. BLT2 antagonist-1 also inhibits the binding of LTB4 and BLT2 with a Ki value of 132 nM. BLT2 antagonist-1 can be used for the research of the inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease[1].

 Names

Name BLT2 antagonist-1

 BLT2 antagonist-1 Biological Activity

Description BLT2 antagonist-1 (compound 15b) is a selective BLT2 antagonist that inhibits the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM. BLT2 antagonist-1 does not inhibits the chemotaxis of CHO-BLT1 cells. BLT2 antagonist-1 also inhibits the binding of LTB4 and BLT2 with a Ki value of 132 nM. BLT2 antagonist-1 can be used for the research of the inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease[1].
Related Catalog
References

[1]. Hyejun Park, et al. Discovery of a novel BLT2 antagonist for the treatment of inflammatory airway diseases. Eur J Med Chem. 2023 Oct 7:261:115864.  

 Chemical & Physical Properties

Molecular Formula C26H26FNO4
Molecular Weight 435.49
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