2069220-61-5

2069220-61-5 structure
2069220-61-5 structure
  • Name: BLT2 antagonist-1
  • Chemical Name: BLT2 antagonist-1
  • CAS Number: 2069220-61-5
  • Molecular Formula: C26H26FNO4
  • Molecular Weight: 435.49
  • Catalog: Signaling Pathways GPCR/G Protein Leukotriene Receptor
  • Create Date: 2024-01-09 16:12:12
  • Modify Date: 2025-08-24 19:57:28
  • BLT2 antagonist-1 (compound 15b) is a selective BLT2 antagonist that inhibits the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM. BLT2 antagonist-1 does not inhibits the chemotaxis of CHO-BLT1 cells. BLT2 antagonist-1 also inhibits the binding of LTB4 and BLT2 with a Ki value of 132 nM. BLT2 antagonist-1 can be used for the research of the inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease[1].

Name BLT2 antagonist-1
Description BLT2 antagonist-1 (compound 15b) is a selective BLT2 antagonist that inhibits the chemotaxis of CHO-BLT2 cells with an IC50 of 224 nM. BLT2 antagonist-1 does not inhibits the chemotaxis of CHO-BLT1 cells. BLT2 antagonist-1 also inhibits the binding of LTB4 and BLT2 with a Ki value of 132 nM. BLT2 antagonist-1 can be used for the research of the inflammatory airway diseases such as asthma and chronic obstructive pulmonary disease[1].
Related Catalog
References

[1]. Hyejun Park, et al. Discovery of a novel BLT2 antagonist for the treatment of inflammatory airway diseases. Eur J Med Chem. 2023 Oct 7:261:115864.  

Molecular Formula C26H26FNO4
Molecular Weight 435.49
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