(2R)-Pinocembrin

Modify Date: 2025-08-26 12:26:32

(2R)-Pinocembrin Structure
(2R)-Pinocembrin structure
Common Name (2R)-Pinocembrin
CAS Number 206660-42-6 Molecular Weight 256.25300
Density N/A Boiling Point N/A
Molecular Formula C15H12O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (2R)-Pinocembrin


(-)-Pinocembrin exhibits anti-mycobacterium activity against mycobacteriuum tuberculosis H37Ra with an IC50 value of 1.11 mg/mL in dormant phase and 1.21 mg/mL in active phase, respectively. (-)-Pinocembrin has potent antiproliferative activity with IC50 values of 1.88-11.00 mg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines[1].

 Names

Name (2R)-5,7-dihydroxy-2-phenyl-2,3-dihydrochromen-4-one

 (2R)-Pinocembrin Biological Activity

Description (-)-Pinocembrin exhibits anti-mycobacterium activity against mycobacteriuum tuberculosis H37Ra with an IC50 value of 1.11 mg/mL in dormant phase and 1.21 mg/mL in active phase, respectively. (-)-Pinocembrin has potent antiproliferative activity with IC50 values of 1.88-11.00 mg/mL against THP-1, A549, Panc-1, HeLa and MCF7 cell lines[1].
Related Catalog
References

[1]. Madhukar S Said, et al. A new butenolide cinnamate and other biological active chemical constituents from Polygonum glabrum. Nat Prod Res. 2015;29(22):2080-6.  

 Chemical & Physical Properties

Molecular Formula C15H12O4
Molecular Weight 256.25300
Exact Mass 256.07400
PSA 66.76000
LogP 2.80430
InChIKey URFCJEUYXNAHFI-CYBMUJFWSA-N
SMILES O=C1CC(c2ccccc2)Oc2cc(O)cc(O)c21
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