DMTr-LNA-C(Bz)-3-CED-phosphoramidite

Modify Date: 2025-08-26 10:18:58

DMTr-LNA-C(Bz)-3-CED-phosphoramidite Structure
DMTr-LNA-C(Bz)-3-CED-phosphoramidite structure
Common Name DMTr-LNA-C(Bz)-3-CED-phosphoramidite
CAS Number 206055-78-9 Molecular Weight 861.92
Density N/A Boiling Point N/A
Molecular Formula C47H52N5O9P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of DMTr-LNA-C(Bz)-3-CED-phosphoramidite


DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name DMTr-LNA-C(Bz)-3-CED-phosphoramidite

 DMTr-LNA-C(Bz)-3-CED-phosphoramidite Biological Activity

Description DMTr-LNA-C(Bz)-3-CED-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C47H52N5O9P
Molecular Weight 861.92
InChIKey SSGINSHBUWKRHC-XCHZTBEFSA-N
SMILES COc1ccc(C(OCC23COC(C(n4ccc(NC(=O)c5ccccc5)nc4=O)O2)C3OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1
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