4-Methyl-1,3-thiazole-5-carboxylic acid

Modify Date: 2024-01-02 17:30:35

4-Methyl-1,3-thiazole-5-carboxylic acid Structure
4-Methyl-1,3-thiazole-5-carboxylic acid structure
Common Name 4-Methyl-1,3-thiazole-5-carboxylic acid
CAS Number 20485-41-0 Molecular Weight 143.164
Density 1.4±0.1 g/cm3 Boiling Point 303.6±22.0 °C at 760 mmHg
Molecular Formula C5H5NO2S Melting Point 287 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 137.4±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name 4-methyl-1,3-thiazole-5-carboxylic acid
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 303.6±22.0 °C at 760 mmHg
Melting Point 287 °C (dec.)(lit.)
Molecular Formula C5H5NO2S
Molecular Weight 143.164
Flash Point 137.4±22.3 °C
Exact Mass 143.004105
PSA 78.43000
LogP 0.58
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.599
Storage condition Room temperature.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
XJ3680000
CHEMICAL NAME :
5-Thiazolecarboxylic acid, 4-methyl-
CAS REGISTRY NUMBER :
20485-41-0
BEILSTEIN REFERENCE NO. :
0120745
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C5-H5-N-O2-S
MOLECULAR WEIGHT :
143.17
WISWESSER LINE NOTATION :
T5N CSJ DVQ E1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1350 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
THERAP Therapie. (Doin, Editeurs, 8, Place de l'Odeon, F-75006 Paris, France) V.1- 1946- Volume(issue)/page/year: 26,497,1971

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H317
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi:Irritant;
Risk Phrases R36/37/38
Safety Phrases S37/39-S26
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS XJ3680000
HS Code 2934100090

 Synthetic Route

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4-Methyl-1,3-thiazole-5-carboxylic acid Structure

4-Methyl-1,3-th...

CAS#:20485-41-0

Literature: Journal of the Chemical Society, , p. 1030

~15%

4-Methyl-1,3-thiazole-5-carboxylic acid Structure

4-Methyl-1,3-th...

CAS#:20485-41-0

Literature: Bulletin of the Chemical Society of Japan, , vol. 77, # 9 p. 1745 - 1755

~%

4-Methyl-1,3-thiazole-5-carboxylic acid Structure

4-Methyl-1,3-th...

CAS#:20485-41-0

Literature: Journal of the American Chemical Society, , vol. 57, p. 1849 Bulletin of the Agricultural Chemical Society of Japan, , vol. 13, p. 47 Chem.Abstr., , p. 7435

~%

4-Methyl-1,3-thiazole-5-carboxylic acid Structure

4-Methyl-1,3-th...

CAS#:20485-41-0

Literature: Journal of Organic Chemistry, , vol. 25, p. 1336 - 1342

~%

4-Methyl-1,3-thiazole-5-carboxylic acid Structure

4-Methyl-1,3-th...

CAS#:20485-41-0

Literature: Journal of the Chemical Society, , p. 601

 Customs

HS Code 2934100090
Summary 2934100090 other compounds containing an unfused thiazole ring (whether or not hydrogenated) in the structure VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

 Synonyms

4-methyl-1,3-thiadiazole-5-carboxylic acid
4-Methyl-1H-thiazole-5-carboxylic acid
MFCD00626872
4-Methyl-thiazol-5-carbonsaeure
4-Methyl-5-thiazolecarboxylic acid
4-Methyl-1,3-thiazole-5-carboxylic acid
4-Methylthiazole-5-carboxylic acid
4-methylthiazole-5-carboxylicacid
5-Thiazolecarboxylic acid, 4-methyl-
4-Methyl-thiazole-5-carboxylic acid
5-Thiazolecarboxylic acid,4-methyl