4-Hydroxychalcone
4-Hydroxychalcone structure
|
Common Name | 4-Hydroxychalcone | ||
|---|---|---|---|---|
| CAS Number | 20426-12-4 | Molecular Weight | 224.25500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H12O2 | Melting Point | 180-184 °C | |
| MSDS | N/A | Flash Point | N/A | |
Use of 4-Hydroxychalcone4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity[1]. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice[2]. |
| Name | 4-hydroxychalcone |
|---|---|
| Synonym | More Synonyms |
| Description | 4-Hydroxychalcone is a chalcone metabolite with anti-angiogenic and anti-inflammatory activities. 4-Hydroxychalcone suppresses angiogenesis by suppression of growth factor pathway with no signs of cytotoxicity[1]. 4-Hydroxychalcone inhibits TNF-α induced NF-κB pathway activation and activates BMP signaling, reduces resistant hypertension (RH) by attenuating hyperaldosteronism and renal injury in mice[2]. |
|---|---|
| Related Catalog | |
| Target |
NF-κB[2] |
| References |
| Melting Point | 180-184 °C |
|---|---|
| Molecular Formula | C15H12O2 |
| Molecular Weight | 224.25500 |
| Exact Mass | 224.08400 |
| PSA | 37.30000 |
| LogP | 3.28830 |
| Hazard Codes | Xi |
|---|---|
| Risk Phrases | R36/37/38:Irritating to eyes, respiratory system and skin . |
| Safety Phrases | S37/39-S26 |
| RIDADR | 3077.0 |
| RTECS | UD1675000 |
| Hazard Class | 9.0 |
| HS Code | 2914501900 |
|
~97%
4-Hydroxychalcone CAS#:20426-12-4 |
| Literature: Rafiee, Ezzat; Rahimi, Farzaneh Journal of the Chilean Chemical Society, 2013 , vol. 58, # 3 p. 1926 - 1929 |
|
~99%
4-Hydroxychalcone CAS#:20426-12-4 |
| Literature: Gavande, Navnath S.; Kundu, Sonia; Badgujar, Naresh S.; Kaur, Gurmeet; Chakraborti, Asit K. Tetrahedron, 2006 , vol. 62, # 17 p. 4201 - 4204 |
|
~53%
4-Hydroxychalcone CAS#:20426-12-4 |
| Literature: Lin; Yu; Zhang Synthetic Communications, 1993 , vol. 23, # 3 p. 271 - 276 |
|
~35%
4-Hydroxychalcone CAS#:20426-12-4 |
| Literature: Graven, Anette; Grotli, Morten; Meldal, Morten Journal of the Chemical Society, Perkin Transactions 1, 2000 , # 6 p. 955 - 962 |
| Precursor 5 | |
|---|---|
| DownStream 5 | |
CAS#:614-47-1
CAS#:17791-25-2
CAS#:74629-69-9| HS Code | 2914501900 |
|---|---|
| Summary | 2914501900 other ketone-phenols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0% |
| 4-HYDROXYBENZYLIDENEACETOPHENONE |
| 2-(4-Hydroxybenzylidene)acetophenone |
| 2-(4-Hydroxybenzal)acetophenone |
| 4-HYDROXYCHALCONE |
| MFCD00016488 |
| HYDROXYCHALCONE,4 |
| BENZYLIDENE-4-HYDROXYACETOPHENONE |
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- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 4-Hydroxychalcone
- Price: Check
- Purity: 95.0%
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- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 4-Hydroxychalcone
- Price: ￥658.0/100mg
- Purity: 98.0%
- Delivery: 1 Day
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- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 4-Hydroxychalcone
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Delivery: Inquiry
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