EDTA-d16

Modify Date: 2024-01-02 00:00:10

EDTA-d16 structure	Common Name	EDTA-d16
	CAS Number	203805-96-3	Molecular Weight	308.341
	Density	1.6±0.1 g/cm3	Boiling Point	614.2±55.0 °C at 760 mmHg
	Molecular Formula	C₁₀D₁₆N₂O₈	Melting Point	N/A
	MSDS	N/A	Flash Point	325.2±31.5 °C

Use of EDTA-d16

Ethylenediaminetetraacetic acid-d16 is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].

Name	ethylenediaminetetraacetic acid-d16
Synonym	More Synonyms

Description	Ethylenediaminetetraacetic acid-d16 is the deuterium labeled Ethylenediaminetetraacetic acid[1]. Ethylenediaminetetraacetic acid (EDTA) is a metal chelators (binds to metal divalent and trivalent cations including calcium), which shows activities of anticoagulant and anti-hypercalcemic. Ethylenediaminetetraacetic acid decreases the metal ion-catalyzed oxidative damage to proteins, and allows maintenance of reducing environment during protein purification. Ethylenediaminetetraacetic acid can also decrease the formation of disulfide bonds[2][3][4].
Related Catalog	Signaling Pathways >> Others >> Others
In Vitro	Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References	[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [2]. Chumanov RS, et al. Artifact-inducing enrichment of ethylenediaminetetraacetic acid and ethyleneglycoltetraacetic acid on anion exchange resins. Anal Biochem. 2011 May 1;412(1):34-9. [3]. Banfi G, et al. The role of ethylenediamine tetraacetic acid (EDTA) as in vitro anticoagulant for diagnostic purposes. Clin Chem Lab Med. 200745(5):565-76. [4]. Ibad A, et al. Chelation therapy in the treatment of cardiovascular diseases. J Clin Lipidol. 2016 Jan-Feb10(1):58-62.

Density	1.6±0.1 g/cm3
Boiling Point	614.2±55.0 °C at 760 mmHg
Molecular Formula	C₁₀D₁₆N₂O₈
Molecular Weight	308.341
Flash Point	325.2±31.5 °C
Exact Mass	308.191101
PSA	155.68000
LogP	-0.43
Vapour Pressure	0.0±3.8 mmHg at 25°C
Index of Refraction	1.580

EDTA-d16

2,2',2'',2'''-[(H)Ethane-1,2-diyldinitrilo]tetra(H)acetic acid

2,2',2'',2'''-[(H)-1,2-Ethanediyldinitrilo]tetra(H)acetic acid

Ethylenediaminetetraacetic Acid-d16

EDTA-d16

Use of EDTA-d16

Names

EDTA-d16 Biological Activity

Chemical & Physical Properties

Synonyms