TAM-16
Modify Date: 2025-08-23 11:10:36
TAM-16 structure
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Common Name | TAM-16 | ||
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| CAS Number | 2030241-59-7 | Molecular Weight | 380.437 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 609.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C22H24N2O4 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 322.7±31.5 °C | |
Use of TAM-16A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13); show highly potent in vitro bactericidal activity against drug-susceptible and drug-resistant clinical isolates of M. tuberculosis (MICs: 0.06-0.25 uM); exhibits in vivo efficacy in multiple mouse models of TB infection, has excellent pharmacological and safety profiles. |
| Name | 5-Hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-(1-piperidinylmethyl)-1-benzofuran-3-carboxamide |
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| Synonym | More Synonyms |
| Description | A benzofuran class inhibitor of M. tuberculosis Pks13 (Polyketide Synthase 13); show highly potent in vitro bactericidal activity against drug-susceptible and drug-resistant clinical isolates of M. tuberculosis (MICs: 0.06-0.25 uM); exhibits in vivo efficacy in multiple mouse models of TB infection, has excellent pharmacological and safety profiles. |
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| References | References 1. Aggarwal A, et al. Cell. 2017 Jul 13;170(2):249-259.e25. View Related Products by Target Bacterial |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 609.9±55.0 °C at 760 mmHg |
| Molecular Formula | C22H24N2O4 |
| Molecular Weight | 380.437 |
| Flash Point | 322.7±31.5 °C |
| Exact Mass | 380.173615 |
| LogP | 1.94 |
| Vapour Pressure | 0.0±1.8 mmHg at 25°C |
| Index of Refraction | 1.652 |
| 5-Hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-(1-piperidinylmethyl)-1-benzofuran-3-carboxamide |
| 3-Benzofurancarboxamide, 5-hydroxy-2-(4-hydroxyphenyl)-N-methyl-4-(1-piperidinylmethyl)- |