Ald-C2-PEG4-azide

Modify Date: 2024-01-03 17:30:09

Ald-C2-PEG4-azide Structure
Ald-C2-PEG4-azide structure
Common Name Ald-C2-PEG4-azide
CAS Number 2030118-14-8 Molecular Weight 275.302
Density N/A Boiling Point N/A
Molecular Formula C11H21N3O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Ald-C2-PEG4-azide


Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name N3-PEG4-CHO
Synonym More Synonyms

 Ald-C2-PEG4-azide Biological Activity

Description Ald-C2-PEG4-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

 Chemical & Physical Properties

Molecular Formula C11H21N3O5
Molecular Weight 275.302
Exact Mass 275.148132
LogP -0.94

 Synonyms

N3-PEG4-ALD
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