Lomitapide Mesylate
Modify Date: 2025-08-26 18:34:33
Lomitapide Mesylate structure
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Common Name | Lomitapide Mesylate | ||
|---|---|---|---|---|
| CAS Number | 202914-84-9 | Molecular Weight | 789.82600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C40H41F6N3O5S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Lomitapide MesylateLomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM.IC50 value: 8 nM [1]Target: MTP inhibitorLomitapide is a small-molecule, microsomal triglyceride transfer protein (MTP) inhibitor, for the treatment of both familial and primary hypercholesterolemia. Oral, once-daily lomitapide will be targeted at patients resistant to HMG-CoA reductase inhibitors (statins) either due to abnormalities in liver function or to discontinuation because of muscle pain. |
| Name | lomitapide mesylate |
|---|---|
| Synonym | More Synonyms |
| Description | Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM.IC50 value: 8 nM [1]Target: MTP inhibitorLomitapide is a small-molecule, microsomal triglyceride transfer protein (MTP) inhibitor, for the treatment of both familial and primary hypercholesterolemia. Oral, once-daily lomitapide will be targeted at patients resistant to HMG-CoA reductase inhibitors (statins) either due to abnormalities in liver function or to discontinuation because of muscle pain. |
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| Related Catalog | |
| References |
[2]. Lomitapide. Am J Cardiovasc Drugs. 2011 Oct 1;11(5):347-52. |
| Molecular Formula | C40H41F6N3O5S |
|---|---|
| Molecular Weight | 789.82600 |
| Exact Mass | 789.26700 |
| PSA | 131.17000 |
| LogP | 10.31990 |
| Storage condition | -20℃ |
| methanesulfonic acid,N-(2,2,2-trifluoroethyl)-9-[4-[4-[[2-[4-(trifluoromethyl)phenyl]benzoyl]amino]piperidin-1-yl]butyl]fluorene-9-carboxamide |
| UNII-X4S83CP54E |
| AEGR-733 |
| Lomitapide mesylate |
| Juxtapid |
| Lomitapide (mesylate) |