N-[(3S)-2-Oxotetrahydro-3-thiophenyl]butanamide

Modify Date: 2024-01-08 13:31:39

N-[(3S)-2-Oxotetrahydro-3-thiophenyl]butanamide Structure
N-[(3S)-2-Oxotetrahydro-3-thiophenyl]butanamide structure
Common Name N-[(3S)-2-Oxotetrahydro-3-thiophenyl]butanamide
CAS Number 202284-85-3 Molecular Weight 187.259
Density 1.2±0.1 g/cm3 Boiling Point 424.6±34.0 °C at 760 mmHg
Molecular Formula C8H13NO2S Melting Point N/A
MSDS N/A Flash Point 210.6±25.7 °C

 Use of N-[(3S)-2-Oxotetrahydro-3-thiophenyl]butanamide


Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. The control of bacterial infection by quenching the quorum sensing system of bacteria is a promising research area. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR protein family, is coordinated by the synthesis of diffusible acyl homoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, a small, diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism . N-butyryl-L-homocysteine thiolactone induces violacein expression in Viola viola mutants that normally fail to produce AHL.

 Names

Name N-[(3S)-2-oxothiolan-3-yl]butanamide
Synonym More Synonyms

  Biological Activity

Description Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. The control of bacterial infection by quenching the quorum sensing system of bacteria is a promising research area. The expression of specific target genes, such as transcriptional regulators belonging to the LuxIR protein family, is coordinated by the synthesis of diffusible acyl homoserine lactone (AHL) molecules. N-butyryl-L-Homocysteine thio-lactone is an analog of N-butyryl-L-homoserine lactone, a small, diffusible signaling molecule involved in quorum sensing, thereby controlling gene expression and cellular metabolism . N-butyryl-L-homocysteine thiolactone induces violacein expression in Viola viola mutants that normally fail to produce AHL.
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 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 424.6±34.0 °C at 760 mmHg
Molecular Formula C8H13NO2S
Molecular Weight 187.259
Flash Point 210.6±25.7 °C
Exact Mass 187.066696
PSA 71.47000
LogP 0.26
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.527

 Synonyms

N-[(3S)-2-Oxotetrahydro-3-thiophenyl]butanamide
N-butyryl-L-Homocysteine thiolactone
Butanamide, N-[(3S)-tetrahydro-2-oxo-3-thienyl]-