C-11

Modify Date: 2024-01-11 18:57:06

Use of C-11

C-11 is a tubulysin-based antibody–drug conjugates (ADCs), displays cytotoxicity for carcinoma cell lines[1].

Name	C-11

Description	C-11 is a tubulysin-based antibody–drug conjugates (ADCs), displays cytotoxicity for carcinoma cell lines[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> Drug-Linker Conjugates for ADC
In Vitro	C-11 exhibits cytotoxicity for N87 cells and MDA-MB-361-DYT2 cells with IC50s of 1.11 nM and 0.9 nM, respectively[1].
References	[1]. Leverett CA, et al. Design, Synthesis, and Cytotoxic Evaluation of Novel Tubulysin Analogues as ADC Payloads. ACS Med Chem Lett. 2016 Aug 26;7(11):999-1004.

Molecular Formula	C₃₈H₅₈N₆O₇S
Molecular Weight	742.97