7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE

Modify Date: 2024-01-10 19:49:35

7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE Structure
7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE structure
Common Name 7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE
CAS Number 20052-60-2 Molecular Weight 206.23800
Density 1.165 g/cm3 Boiling Point 369.2ºC at 760 mmHg
Molecular Formula C12H14O3 Melting Point 189ºC
MSDS N/A Flash Point 144.4ºC

 Names

Name 7-hydroxy-2,2,5-trimethyl-3H-chromen-4-one
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.165 g/cm3
Boiling Point 369.2ºC at 760 mmHg
Melting Point 189ºC
Molecular Formula C12H14O3
Molecular Weight 206.23800
Flash Point 144.4ºC
Exact Mass 206.09400
PSA 46.53000
LogP 2.44440
Vapour Pressure 5.67E-06mmHg at 25°C
Index of Refraction 1.547

 MSDS

Name: 7-Hydroxy-2 2 5-trimethyl-2 3-dihydro-4h-chromen-4-one 97% Material Safety Data Sheet
Synonym: 7-Hydroxy-2,2,5-trimethyl chromanon
CAS: 20052-60-2
Section 1 - Chemical Product MSDS Name:7-Hydroxy-2 2 5-trimethyl-2 3-dihydro-4h-chromen-4-one 97% Material Safety Data Sheet
Synonym:7-Hydroxy-2,2,5-trimethyl chromanon

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
20052-60-2 7-Hydroxy-2,2,5-trimethyl-2,3-dihydro- 97% unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a cool, dry place. Store in a tightly closed container.

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 20052-60-2: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Solid
Color: off-white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: 189 - 191 deg C
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C12H14O3
Molecular Weight: 206

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Not available.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Carbon monoxide, carbon dioxide, acrid smoke and fumes.
Hazardous Polymerization: Not available.

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 20052-60-2 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
7-Hydroxy-2,2,5-trimethyl-2,3-dihydro-4H-chromen-4-one - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
No information available.
IMO
No information available.
RID/ADR
No information available.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 20052-60-2: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 20052-60-2 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 20052-60-2 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Hazard Codes Xi
Risk Phrases R36/37/38
Safety Phrases 26-36/37/39

 Synthetic Route

~89%

7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE Structure

7-HYDROXY-2,2,5...

CAS#:20052-60-2

Literature: Sowmithran, D.; Rajendra Prasad, K. J. Synthesis, 1985 , # 5 p. 545 - 546

~53%

7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE Structure

7-HYDROXY-2,2,5...

CAS#:20052-60-2

Literature: Morales, Paula; Azofra, Luis Miguel; Cumella, Jose; Hernandez-Folgado, Laura; Roldan, Maria; Alkorta, Ibon; Jagerovic, Nadine Arkivoc, 2014 , vol. 2014, # 2 p. 319 - 332

~84%

7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE Structure

7-HYDROXY-2,2,5...

CAS#:20052-60-2

Literature: Ramana, M. M. V.; Kudav, N. A. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1988 , vol. 27, # 1-12 p. 339 - 341

~88%

7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE Structure

7-HYDROXY-2,2,5...

CAS#:20052-60-2

Literature: Acta Chimica Hungarica, , vol. 125, # 3 p. 457 - 464

~90%

7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE Structure

7-HYDROXY-2,2,5...

CAS#:20052-60-2

Literature: Sowmithran, D.; Rajendra Prasad, K. J. Synthesis, 1985 , # 5 p. 545 - 546

~10%

7-HYDROXY-2,2,5-TRIMETHYL-2,3-DIHYDRO-4H-CHROMEN-4-ONE Structure

7-HYDROXY-2,2,5...

CAS#:20052-60-2

Detail
Literature: Indian Journal of Chemistry - Section B Organic Chemistry Including Medicinal Chemistry, , vol. 29, # 7 p. 661 - 663

 Synonyms

7-hydroxy-2,2,5-trimethyl-chroman-4-one
7-Hydroxy-2,2,5-trimethyl-4-chromanone
2,3-Dihydro-7-hydroxy-2,2,5-trimethyl-4H-1-benzopyran-4-one
7-hydroxy-2,2,5-trimethyl-3,4-dihydro-2H-chromen-4-one
7-Hydroxy-2,2,5-trimethyl-2,3-dihydro-4H-chromen-4-one
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