2′-Deoxy-N-methylguanosine

Modify Date: 2025-08-25 15:27:21

2′-Deoxy-N-methylguanosine structure	Common Name	2′-Deoxy-N-methylguanosine
	CAS Number	19916-77-9	Molecular Weight	281.27
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₁H₁₅N₅O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of 2′-Deoxy-N-methylguanosine

2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	(2R,3S,5R)-5-(2-amino-6-methoxypurin-9-yl)-2-(hydroxymethyl)oxolan-3-ol
Synonym	More Synonyms

Description	2’-Deoxy-N2-methylguanosine, DNA adduct is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Molecular Formula	C₁₁H₁₅N₅O₄
Molecular Weight	281.27
Exact Mass	281.11200
PSA	125.29000
InChIKey	XEZUVZDXOQPEKT-RRKCRQDMSA-N
SMILES	CNc1nc2c(ncn2C2CC(O)C(CO)O2)c(=O)[nH]1