Thalidomide-NH-(CH2)2-NH-Boc
Modify Date: 2025-09-22 00:02:38
Thalidomide-NH-(CH2)2-NH-Boc structure
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Common Name | Thalidomide-NH-(CH2)2-NH-Boc | ||
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| CAS Number | 1957235-57-2 | Molecular Weight | 416.43 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C20H24N4O6 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Thalidomide-NH-(CH2)2-NH-BocThalidomide-NH-(CH2)2-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)2-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)2-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules. |
| Name | N-[2-[[2-(2,6-Dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]ethyl]-carbamic Acid 1,1-Dimethylethyl Ester |
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| Description | Thalidomide-NH-(CH2)2-NH-Boc is a Boc-modified Thalidomide (HY-14658) that acts as a Cereblon ligand to recruit CRBN protein. The Boc protecting group at the end of Thalidomide-NH-(CH2)2-NH-Boc can be removed under acidic conditions to participate in the synthesis of PROTAC molecules. Thalidomide-NH-(CH2)2-NH-Boc is a key intermediate in the synthesis of CRBN-based PROTAC molecules. |
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| Related Catalog |
| Molecular Formula | C20H24N4O6 |
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| Molecular Weight | 416.43 |
| Appearance of Characters | Solid | Yellow |
| Water Solubility | Dichloromethane, Ethyl Acetate, Methanol |