Ulixertinib hydrochloride
Modify Date: 2025-08-25 18:58:37
Ulixertinib hydrochloride structure
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Common Name | Ulixertinib hydrochloride | ||
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| CAS Number | 1956366-10-1 | Molecular Weight | 469.79 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H23Cl3N4O2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of Ulixertinib hydrochlorideUlixertinib hydrochloride is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line[1][2]. |
| Name | Ulixertinib hydrochloride |
|---|
| Description | Ulixertinib hydrochloride is a potent, orally active, highly selective, ATP-competitive and reversible covalent inhibitor of ERK1/2 kinases, with an IC50 of <0.3 nM against ERK2. Ulixertinib hydrochloride inhibits the phosphorylated ERK2 (pERK) and downstream kinase RSK (pRSK) in an A375 melanoma cell line[1][2]. |
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| Molecular Formula | C21H23Cl3N4O2 |
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| Molecular Weight | 469.79 |
| InChIKey | DKGYQCPFBWFTHM-FSRHSHDFSA-N |
| SMILES | CC(C)Nc1cc(-c2c[nH]c(C(=O)NC(CO)c3cccc(Cl)c3)c2)c(Cl)cn1.Cl |
| Storage condition | 2-8℃ |