MAK683

Modify Date: 2025-08-25 15:50:08

MAK683 Structure
MAK683 structure
Common Name MAK683
CAS Number 1951408-58-4 Molecular Weight 376.39
Density N/A Boiling Point N/A
Molecular Formula C20H17FN6O Melting Point N/A
MSDS N/A Flash Point N/A

 Use of MAK683


EED inhibitor-1 is an EED inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.

 Names

Name MAK683
Synonym More Synonyms

 MAK683 Biological Activity

Description EED inhibitor-1 is an EED inhibitor extracted from patent US20160176882 A1, compound example 2; has IC50s of 59, 89, 26 nM in EED Alphascreen binding, LC-MS and ELISA assay.
Related Catalog
Target

IC50: 59 nM (EED Alphascreen), 89 nM (LC-MS), 26 nM (ELISA)[1]

In Vitro EED inhibitor-1 has antiproliferative activities in B cell lymphoma cell KARPAS422 after 14 days of treatment with an IC50 of 30 nM[1].
References

[1]. US20160176882 A1

 Chemical & Physical Properties

Molecular Formula C20H17FN6O
Molecular Weight 376.39
Storage condition 2-8℃

 Synonyms

EED inhibitor-1
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