Benzo(c)phenanthrene

Modify Date: 2025-08-23 20:10:10

Benzo(c)phenanthrene Structure
Benzo(c)phenanthrene structure
Common Name Benzo(c)phenanthrene
CAS Number 195-19-7 Molecular Weight 228.288
Density 1.2±0.1 g/cm3 Boiling Point 436.7±12.0 °C at 760 mmHg
Molecular Formula C18H12 Melting Point 158-160℃
MSDS Chinese USA Flash Point 209.1±13.7 °C
Symbol GHS07
GHS07
Signal Word Warning

 Names

Name Benzo[c]phenanthrene
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 436.7±12.0 °C at 760 mmHg
Melting Point 158-160℃
Molecular Formula C18H12
Molecular Weight 228.288
Flash Point 209.1±13.7 °C
Exact Mass 228.093903
LogP 5.91
Vapour Pressure 0.0±0.5 mmHg at 25°C
Index of Refraction 1.771

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
DI8225000
CHEMICAL NAME :
Benzo(c)phenanthrene
CAS REGISTRY NUMBER :
195-19-7
BEILSTEIN REFERENCE NO. :
1909296
LAST UPDATED :
199710
DATA ITEMS CITED :
12
MOLECULAR FORMULA :
C18-H12
MOLECULAR WEIGHT :
228.30
WISWESSER LINE NOTATION :
L C6 B666J

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
940 mg/kg/39W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1220 mg/kg/51W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application
TYPE OF TEST :
TD - Toxic dose (other than lowest)
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1270 mg/kg/53W-I
TOXIC EFFECTS :
Tumorigenic - equivocal tumorigenic agent by RTECS criteria Skin and Appendages - tumors Tumorigenic - tumors at site of application

MUTATION DATA

TEST SYSTEM :
Rodent - mouse
DOSE/DURATION :
80 umol/L
REFERENCE :
CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 17,2237,1996 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,205,1983 IARC Cancer Review:Human No Adequate Data IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 32,205,1983 IARC Cancer Review:Group 3 IMSUDL IARC Monographs, Supplement. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) No.1- 1979- Volume(issue)/page/year: 7,56,1987 TOXICOLOGY REVIEW 85DHAX "Medical and Biologic Effects of Environmental Pollutants Series," Washington, DC, National Academy of Sciences, 1972-77 Volume(issue)/page/year: Pc,4,1972

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302 + H312 + H332-H315-H319-H335
Precautionary Statements P261-P280-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases 20/21/22-36/37/38
Safety Phrases 26-37/39
RIDADR UN 2811
RTECS DI8225000
Packaging Group III
Hazard Class 6.1(b)
HS Code 2902909090

 Synthetic Route

 Customs

HS Code 2902909090
Summary 2902909090 other aromatic hydrocarbons。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:2.0%。General tariff:30.0%

 Articles25

More Articles
Benzo[c]phenanthrene adducts and nogalamycin inhibit DNA transesterification by vaccinia topoisomerase.

J. Biol. Chem. 279(22) , 23335-42, (2004)

Vaccinia DNA topoisomerase forms a covalent DNA-(3'-phosphotyrosyl)-enzyme intermediate at a specific target site 5'-C(+5)C(+4)C(+3)T(+2)T(+1)p downward arrow N(-1) in duplex DNA. Here we study the ef...

In vitro and in vivo modulations of benzo[c]phenanthrene-DNA adducts by DNA mismatch repair system.

Nucleic Acids Res. 31(22) , 6428-34, (2003)

Benzo[c]phenanthrene dihydrodiol epoxide (B[c] PhDE) is well known as an important environmental chemical carcinogen that preferentially modifies DNA in adenine residues. However, the molecular mechan...

Structure/reactivity relationships in the benzo[c]phenanthrene skeleton: stable ion and electrophilic substitution (nitration, bromination) study of substituted analogues, novel carbocations and substituted derivatives.

J. Org. Chem. 72(9) , 3232-41, (2007)

A series of novel carbocations were generated by low-temperature protonation of substituted benzo[c]phenanthrenes, B[c]Phs, and their charge delocalization pathways were elucidated by NMR on the basis...

 Synonyms

Benzo[c]phenanthrene
1S-TRANS-ANTI-BENZO[C]PHENANTHRENE
AR-G 3 BENZO(C)PHENANTHRENE
1R-TRANS-ANTI-BENZO[C]PHENANTHRENE
Benzo(c)phenanthrene
tetrahelicene
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.
Top Suppliers:I want be here



Get all suppliers and price by the below link:

Benzo(c)phenanthrene suppliers

Benzo(c)phenanthrene price