KMH-233
Modify Date: 2025-11-24 18:27:37
KMH-233 structure
|
Common Name | KMH-233 | ||
|---|---|---|---|---|
| CAS Number | 1941174-13-5 | Molecular Weight | 587.58 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C32H25N7O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of KMH-233KMH-233, a potent, reversible and selective l-type amino acid transporter 1 (LAT1), inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM). |
| Name | KMH-233 |
|---|
| Description | KMH-233, a potent, reversible and selective l-type amino acid transporter 1 (LAT1), inhibits the uptake of LAT1 substrate, l-leucin (IC50=18 μM) as well as cell growth. KMH-233 significantly potentiates the efficacy of Bestatin and Cisplatin even at low concentrations (25 μM). |
|---|
| Molecular Formula | C32H25N7O5 |
|---|---|
| Molecular Weight | 587.58 |
| InChIKey | MLNOOVGSMCJSCE-DEOSSOPVSA-N |
| SMILES | CNC(=O)COc1ccc(-c2c(C#N)c(NC(=O)c3cccc(CC(N)C(=O)O)c3)n3c(nc4ccccc43)c2C#N)cc1 |