5’-Azido-5’-deoxy-2’-O-methyluridine

Modify Date: 2024-03-04 22:26:44

5’-Azido-5’-deoxy-2’-O-methyluridine Structure
5’-Azido-5’-deoxy-2’-O-methyluridine structure
Common Name 5’-Azido-5’-deoxy-2’-O-methyluridine
CAS Number 194034-68-9 Molecular Weight 269.21
Density N/A Boiling Point N/A
Molecular Formula C9H11N5O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 5’-Azido-5’-deoxy-2’-O-methyluridine


5’-Azido-5’-deoxy-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1-[(2R,3R,4R,5R)-5-(azidomethyl)-4-hydroxy-3-methoxyoxolan-2-yl]pyrimidine-2,4-dione
Synonym More Synonyms

 5’-Azido-5’-deoxy-2’-O-methyluridine Biological Activity

Description 5’-Azido-5’-deoxy-2’-O-methyluridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C9H11N5O5
Molecular Weight 269.21
Exact Mass 283.09200
PSA 143.56000

 Synonyms

Uridine,5'-azido-5'-deoxy-2'-O-methyl
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