(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol

Modify Date: 2025-09-19 17:08:54

(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol Structure
(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol structure
Common Name (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol
CAS Number 190315-43-6 Molecular Weight 150.20
Density N/A Boiling Point N/A
Molecular Formula C5H10O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol


(2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 1,4-anhydro-4-thio-D-ribitol
Synonym More Synonyms

  Biological Activity

Description (2R,3S,4R)-2-(Hydroxymethyl)tetrahydrothiophene-3,4-diol is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C5H10O3S
Molecular Weight 150.20
Exact Mass 150.03500
PSA 85.99000
InChIKey VLVSFIRYIVAVKW-LMVFSUKVSA-N
SMILES OCC1SCC(O)C1O

 Synonyms

(2R,3S,4R)-2-Hydroxymethyl-tetrahydro-thiophene-3,4-diol
1,4-anhydro-4-thio-D-ribose
(+)-1-deoxy-4-thio-D-ribose
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