Ophiobolin C

Modify Date: 2025-08-25 19:33:31

Ophiobolin C structure	Common Name	Ophiobolin C
	CAS Number	19022-51-6	Molecular Weight	386.57
	Density	1.064g/cm3	Boiling Point	512.4ºC at 760mmHg
	Molecular Formula	C₂₅H₃₈O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	277.8ºC

Use of Ophiobolin C

Ophiobolin C inhibits CCR5 binding to the envelop protein gp120 and CD4, which is responsible for mediating the entry of HIV-1 into cells[1]. Ophiobolin C is also cytotoxic to chronic lymphocytic leukemia cells[2].

Name	ophiobolin C
Synonym	More Synonyms

Description	Ophiobolin C inhibits CCR5 binding to the envelop protein gp120 and CD4, which is responsible for mediating the entry of HIV-1 into cells[1]. Ophiobolin C is also cytotoxic to chronic lymphocytic leukemia cells[2].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> CCR Signaling Pathways >> Anti-infection >> HIV Research Areas >> Infection Signaling Pathways >> Immunology/Inflammation >> CCR
References	[1]. Jayasuriya H, et al. Isolation and structure of antagonists of chemokine receptor (CCR5). J Nat Prod. 2004 Jun;67(6):1036-8. [2]. Bladt TT, et al. Bio-activity and dereplication-based discovery of ophiobolins and other fungal secondary metabolites targeting leukemia cells. Molecules. 2013 Nov 26;18(12):14629-50.

Description

Related Catalog

Signaling Pathways >> GPCR/G Protein >> CCR

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

Signaling Pathways >> Immunology/Inflammation >> CCR

References

[1]. Jayasuriya H, et al. Isolation and structure of antagonists of chemokine receptor (CCR5). J Nat Prod. 2004 Jun;67(6):1036-8.

[2]. Bladt TT, et al. Bio-activity and dereplication-based discovery of ophiobolins and other fungal secondary metabolites targeting leukemia cells. Molecules. 2013 Nov 26;18(12):14629-50.

Density	1.064g/cm3
Boiling Point	512.4ºC at 760mmHg
Molecular Formula	C₂₅H₃₈O₃
Molecular Weight	386.57
Flash Point	277.8ºC
Exact Mass	386.28200
PSA	54.37000
LogP	5.27670
Vapour Pressure	1.21E-12mmHg at 25°C
Index of Refraction	1.544

3-Hydroxy-5-oxoophiobola-7,19-dien-25-al

Ophiobolin C-Triol

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Ophiobolin C
Price: Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: ophiobolin C
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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Ophiobolin C

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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.