(R)-(-)-NIGULDIPINE HYDROCHLORIDE

Modify Date: 2025-09-13 19:24:11

(R)-(-)-NIGULDIPINE HYDROCHLORIDE structure	Common Name	(R)-(-)-NIGULDIPINE HYDROCHLORIDE
	CAS Number	189624-85-9	Molecular Weight	759.71700
	Density	N/A	Boiling Point	780.5ºC at 760 mmHg
	Molecular Formula	C₄₁H₄₄Cl₂N₄O₆	Melting Point	N/A
	MSDS	N/A	Flash Point	425.8ºC

Name	5-O-ethenyl 3-O-methyl (2S)-2-[4-(4-benzhydrylpiperazin-1-yl)phenyl]-2,6-dimethyl-4-(3-nitrophenyl)-3,4-dihydro-1H-pyridine-3,5-dicarboxylate,dihydrochloride
Synonym	More Synonyms

Boiling Point	780.5ºC at 760 mmHg
Molecular Formula	C₄₁H₄₄Cl₂N₄O₆
Molecular Weight	759.71700
Flash Point	425.8ºC
Exact Mass	758.26400
PSA	116.93000
LogP	9.31740
Vapour Pressure	2.62E-24mmHg at 25°C

CHEMICAL IDENTIFICATION

RTECS NUMBER :: US7201200

CHEMICAL NAME :: 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-(4-(4- (diphenylmethyl)-1-piperazinyl)phenyl)ethyl methyl ester, dihydrochloride, (S)-(+)-

CAS REGISTRY NUMBER :: 189624-85-9

LAST UPDATED :: 199806

DATA ITEMS CITED :: 2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: >12 mg/kg

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - conjunctive irritation Behavioral - somnolence (general depressed activity) Lungs, Thorax, or Respiration - dyspnea

REFERENCE :: YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 25(Suppl 3),S745,1997 ** OTHER MULTIPLE DOSE TOXICITY DATA **

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 14850 ug/kg/9D-I

TOXIC EFFECTS :: Liver - hepatitis (hepatocellular necrosis), diffuse Blood - normocytic anemia Related to Chronic Data - death

REFERENCE :: YACHDS Yakuri to Chiryo. Pharmacology and Therapeutics. (Raifu Saiensu Shuppan K.K., 2-5-13, Yaesu, Chuo-ku, Tokyo 104, Japan) V.1- 1972- Volume(issue)/page/year: 25(Suppl 3),S793,1997

(S)-(+)-Watanidipine hydrochloride

BY 935

Watanidipine hydrochloride (S)-enantiomer

(S)-AE0047

(R)-Nigaldipine hydrochloride

3,5-Pyridinedicarboxylic acid,1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-,2-(4-(4-(diphenylmethyl)-1-piperazinyl)phenyl)ethyl methyl ester,dihydrochloride,(S)-(+)

(-)-Nigaldipine hydrochloride

B 8509-035

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(R)-(-)-NIGULDIPINE HYDROCHLORIDE

Names

Chemical & Physical Properties

Toxicological Information

CHEMICAL IDENTIFICATION

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

Synonyms

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.