1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE

Modify Date: 2024-01-17 19:46:28

1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE Structure
1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE structure
Common Name 1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE
CAS Number 18956-16-6 Molecular Weight 270.28000
Density 1.282g/cm3 Boiling Point 484.5ºC at 760 mmHg
Molecular Formula C16H14O4 Melting Point N/A
MSDS N/A Flash Point 182.7ºC

 Use of 1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE


Cardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway[1].

 Names

Name cardamonin
Synonym More Synonyms

  Biological Activity

Description Cardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway[1].
Related Catalog
Target

NLRP3

References

[1]. Wang K, et al. Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway. Biochem Pharmacol. 2018 Sep;155:494-509.

 Chemical & Physical Properties

Density 1.282g/cm3
Boiling Point 484.5ºC at 760 mmHg
Molecular Formula C16H14O4
Molecular Weight 270.28000
Flash Point 182.7ºC
Exact Mass 270.08900
PSA 66.76000
LogP 3.00250
Vapour Pressure 5.2E-10mmHg at 25°C
Index of Refraction 1.657
Storage condition 2-8°C

 Synonyms

2',4'-dihydroxy-6'-methoxychalkone
Alpinetinchalkon
4',6'-dihydroxy-2'-methoxychalcone
2',4'-Dihydroxy-6'-methoxychalkon
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