18956-16-6

18956-16-6 structure

Name: 1-(2,4-DIHYDROXY-6-METHOXYPHENYL)-3-PHENYLPROP-2-EN-1-ONE
Chemical Name: cardamonin
CAS Number: 18956-16-6
Molecular Formula: C₁₆H₁₄O₄
Molecular Weight: 270.28000
Catalog: Signaling Pathways Immunology/Inflammation Aryl Hydrocarbon Receptor
Create Date: 2018-10-01 00:05:17
Modify Date: 2025-08-25 09:08:13
Cardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway[1].

Name	cardamonin
Synonyms	2',4'-dihydroxy-6'-methoxychalkone Alpinetinchalkon 4',6'-dihydroxy-2'-methoxychalcone 2',4'-Dihydroxy-6'-methoxychalkon

Description	Cardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway[1].
Related Catalog	Signaling Pathways >> Immunology/Inflammation >> Aryl Hydrocarbon Receptor Signaling Pathways >> Immunology/Inflammation >> NOD-like Receptor (NLR) Research Areas >> Inflammation/Immunology
Target	NLRP3
References	[1]. Wang K, et al. Cardamonin, a natural flavone, alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway. Biochem Pharmacol. 2018 Sep;155:494-509.