TBK1/IKKε-IN-1(compound 1)

Modify Date: 2024-01-09 19:06:43

TBK1/IKKε-IN-1(compound 1) Structure
TBK1/IKKε-IN-1(compound 1) structure
Common Name TBK1/IKKε-IN-1(compound 1)
CAS Number 1893397-65-3 Molecular Weight 513.59
Density N/A Boiling Point N/A
Molecular Formula C28H31N7O3 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of TBK1/IKKε-IN-1(compound 1)


TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively[1].

 Names

Name TBK1/IKKε-IN-5

 TBK1/IKKε-IN-1(compound 1) Biological Activity

Description TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively[1].
Related Catalog
Target

IC50: 1 nM (TBK1), 5.6 nM (IKKε)[1].

References

[1]. Jenkins RW, et al. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018 Feb;8(2):196-215.

 Chemical & Physical Properties

Molecular Formula C28H31N7O3
Molecular Weight 513.59