TBK1/IKKε-IN-1(compound 1)

Modify Date: 2025-08-27 12:10:40

TBK1/IKKε-IN-1(compound 1) structure	Common Name	TBK1/IKKε-IN-1(compound 1)
	CAS Number	1893397-65-3	Molecular Weight	513.59
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₈H₃₁N₇O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TBK1/IKKε-IN-1(compound 1)

TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively[1].

Name	TBK1/IKKε-IN-5

Description	TBK1/IKKε-IN-5 (compound 1) is a dual TBK1 and IKKε inhibitor, with IC50 values of 1 nM and 5.6 nM for TBK1 and IKKε, respectively[1].
Related Catalog	Signaling Pathways >> NF-κB >> IKK Research Areas >> Cancer
Target	IC50: 1 nM (TBK1), 5.6 nM (IKKε)[1].
References	[1]. Jenkins RW, et al. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids. Cancer Discov. 2018 Feb;8(2):196-215.

Molecular Formula	C₂₈H₃₁N₇O₃
Molecular Weight	513.59
InChIKey	QYQFLAQHGHBIFA-UHFFFAOYSA-N
SMILES	N#Cc1cc(-c2ncnc(Nc3ccc(N4CCN(C5COC5)CC4)cc3)n2)ccc1OC1CCOCC1

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: TBK1/IKKε-IN-5
Price: Check
Purity: 98.0%
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ShangHai DC Chemicals Co.,Ltd
China
Product Name: TBK1/IKKε-IN-5
Price: ￥Inquiry/1g
Purity: 98.9%
Delivery: 1 Day
Contact: Tony Lai
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DC Chemicals Limited
China
Product Name: TBK1/IKKε-IN-5
Price: $850.0/100mg $1650.0/250mg $3150.0/1g ￥220.0/10ml
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
Email: sales@dcchemicals.com

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