ASN90

Modify Date: 2025-08-26 06:54:16

ASN90 Structure
ASN90 structure
Common Name ASN90
CAS Number 1884154-02-2 Molecular Weight 375.45
Density N/A Boiling Point N/A
Molecular Formula C17H21N5O3S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ASN90


ASN90 is a specific and orally active O-GlcNAcase (OGA) enzyme inhibitor with IC50 value of 10.2 nM. ASN90 can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies[1].

 Names

Name ASN90

 ASN90 Biological Activity

Description ASN90 is a specific and orally active O-GlcNAcase (OGA) enzyme inhibitor with IC50 value of 10.2 nM. ASN90 can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies[1].
Related Catalog
References

[1]. Permanne B, et al. O-GlcNAcase Inhibitor ASN90 is a Multimodal Drug Candidate for Tau and α-Synuclein Proteinopathies. ACS Chem Neurosci. 2022 Apr 20;13(8):1296-1314.  

 Chemical & Physical Properties

Molecular Formula C17H21N5O3S
Molecular Weight 375.45
InChIKey PLUUAFJXXNCXSD-NSHDSACASA-N
SMILES CC(=O)Nc1nnc(N2CCN(C(C)c3ccc4c(c3)OCO4)CC2)s1
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