N2-(tert-Butoxycarbonyl)-L-α-glutamine

Modify Date: 2024-01-04 16:50:24

N2-(tert-Butoxycarbonyl)-L-α-glutamine Structure
N2-(tert-Butoxycarbonyl)-L-α-glutamine structure
Common Name N2-(tert-Butoxycarbonyl)-L-α-glutamine
CAS Number 18800-74-3 Molecular Weight 246.260
Density 1.2±0.1 g/cm3 Boiling Point 495.3±40.0 °C at 760 mmHg
Molecular Formula C10H18N2O5 Melting Point 116-120ºC
MSDS N/A Flash Point 253.3±27.3 °C

 Names

Name boc-glu-nh2
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 495.3±40.0 °C at 760 mmHg
Melting Point 116-120ºC
Molecular Formula C10H18N2O5
Molecular Weight 246.260
Flash Point 253.3±27.3 °C
Exact Mass 246.121567
PSA 118.72000
LogP 0.11
Vapour Pressure 0.0±2.7 mmHg at 25°C
Index of Refraction 1.495
Storage condition Store at RT.

 MSDS

Name: BOC-L-Isoglutamine Material Safety Data Sheet
Synonym: N-(tert-Butoxycarbonyl)-L-isoglutamin
CAS: 18800-74-3
Section 1 - Chemical Product MSDS Name:BOC-L-Isoglutamine Material Safety Data Sheet
Synonym:N-(tert-Butoxycarbonyl)-L-isoglutamin

Section 2 - COMPOSITION, INFORMATION ON INGREDIENTS
CAS# Chemical Name content EINECS#
18800-74-3 BOC-L-Isoglutamine unlisted
Hazard Symbols: None Listed.
Risk Phrases: None Listed.

Section 3 - HAZARDS IDENTIFICATION
EMERGENCY OVERVIEW
Not available.
Potential Health Effects
Eye:
May cause eye irritation.
Skin:
May cause skin irritation. May be harmful if absorbed through the skin.
Ingestion:
May cause irritation of the digestive tract. May be harmful if swallowed.
Inhalation:
May cause respiratory tract irritation. May be harmful if inhaled.
Chronic:
Not available.

Section 4 - FIRST AID MEASURES
Eyes: Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes.
Ingestion:
Get medical aid. Wash mouth out with water.
Inhalation:
Remove from exposure and move to fresh air immediately.
Notes to Physician:
Treat symptomatically and supportively.

Section 5 - FIRE FIGHTING MEASURES
General Information:
As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear.
Extinguishing Media:
Use water spray, dry chemical, carbon dioxide, or chemical foam.

Section 6 - ACCIDENTAL RELEASE MEASURES
General Information: Use proper personal protective equipment as indicated in Section 8.
Spills/Leaks:
Vacuum or sweep up material and place into a suitable disposal container.

Section 7 - HANDLING and STORAGE
Handling:
Avoid breathing dust, vapor, mist, or gas. Avoid contact with skin and eyes.
Storage:
Store in a tightly closed container. Store in a dry area. Keep refrigerated. (Store below 4C/39F.)

Section 8 - EXPOSURE CONTROLS, PERSONAL PROTECTION
Engineering Controls:
Use adequate ventilation to keep airborne concentrations low.
Exposure Limits CAS# 18800-74-3: Personal Protective Equipment Eyes: Not available.
Skin:
Wear appropriate protective gloves to prevent skin exposure.
Clothing:
Wear appropriate protective clothing to prevent skin exposure.
Respirators:
Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.

Section 9 - PHYSICAL AND CHEMICAL PROPERTIES

Physical State: Powder
Color: white
Odor: Not available.
pH: Not available.
Vapor Pressure: Not available.
Viscosity: Not available.
Boiling Point: Not available.
Freezing/Melting Point: Not available.
Autoignition Temperature: Not available.
Flash Point: Not available.
Explosion Limits, lower: Not available.
Explosion Limits, upper: Not available.
Decomposition Temperature:
Solubility in water:
Specific Gravity/Density:
Molecular Formula: C10H18N2O5
Molecular Weight: 246.26

Section 10 - STABILITY AND REACTIVITY
Chemical Stability:
Stable.
Conditions to Avoid:
Incompatible materials.
Incompatibilities with Other Materials:
Strong oxidizing agents.
Hazardous Decomposition Products:
Nitrogen oxides, carbon monoxide, carbon dioxide.
Hazardous Polymerization: Has not been reported

Section 11 - TOXICOLOGICAL INFORMATION
RTECS#:
CAS# 18800-74-3 unlisted.
LD50/LC50:
Not available.
Carcinogenicity:
BOC-L-Isoglutamine - Not listed by ACGIH, IARC, or NTP.

Section 12 - ECOLOGICAL INFORMATION


Section 13 - DISPOSAL CONSIDERATIONS
Dispose of in a manner consistent with federal, state, and local regulations.

Section 14 - TRANSPORT INFORMATION

IATA
Not regulated as a hazardous material.
IMO
Not regulated as a hazardous material.
RID/ADR
Not regulated as a hazardous material.

Section 15 - REGULATORY INFORMATION

European/International Regulations
European Labeling in Accordance with EC Directives
Hazard Symbols: Not available.
Risk Phrases:
Safety Phrases:
S 24/25 Avoid contact with skin and eyes.
WGK (Water Danger/Protection)
CAS# 18800-74-3: No information available.
Canada
None of the chemicals in this product are listed on the DSL/NDSL list.
CAS# 18800-74-3 is not listed on Canada's Ingredient Disclosure List.
US FEDERAL
TSCA
CAS# 18800-74-3 is not listed on the TSCA inventory.
It is for research and development use only.


SECTION 16 - ADDITIONAL INFORMATION
N/A

 Safety Information

Safety Phrases S24/25
HS Code 2924199090

 Synthetic Route

~%

N2-(tert-Butoxycarbonyl)-L-α-glutamine Structure

N2-(tert-Butoxy...

CAS#:18800-74-3

Literature: EP2543660 A1, ; Paragraph 0123 ;

 Precursor & DownStream

Precursor  2

DownStream  0

 Customs

HS Code 2924199090
Summary 2924199090. other acyclic amides (including acyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

 Synonyms

t-butoxycarbonyl-L-tyrosine ethyl ester
N-{[(2-Methyl-2-propanyl)oxy]carbonyl}-L-α-glutamine
Boc-L-Tyr-OEt
N-Boc-L-tyrosine ethyl ester
4-tert-Butoxycarbonylamino-4-carbamoylbutyric acid
Boc-L-Glu-NH2
N-(tert-Butoxycarbonyl)-L-α-glutamine
Dach platinum dinitrate
Boc-Tyr-OEt
MFCD00070081
Boc-L-Tyrosine ethyl ester
Boc-isoGln-OH