(S,E)-Ethyl 4-((S)-2-((Tert-Butoxycarbonyl)Amino)-N,3,3-Trimethylbutanamido)-2,5-Dimethylhex-2-Enoate
Modify Date: 2024-04-05 13:39:25
(S,E)-Ethyl 4-((S)-2-((Tert-Butoxycarbonyl)Amino)-N,3,3-Trimethylbutanamido)-2,5-Dimethylhex-2-Enoate structure
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Common Name | (S,E)-Ethyl 4-((S)-2-((Tert-Butoxycarbonyl)Amino)-N,3,3-Trimethylbutanamido)-2,5-Dimethylhex-2-Enoate | ||
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| CAS Number | 187345-37-5 | Molecular Weight | 412.56 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 511.2±45.0 °C at 760 mmHg | |
| Molecular Formula | C22H40N2O5 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | 263.0±28.7 °C | |
Use of (S,E)-Ethyl 4-((S)-2-((Tert-Butoxycarbonyl)Amino)-N,3,3-Trimethylbutanamido)-2,5-Dimethylhex-2-EnoateTaltobulin intermediate-4 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1]. |
| Name | 2-Hexenoic acid, 4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3,3-dimethyl-1-oxobutyl]methylamino]-2,5-dimethyl-, ethyl ester, (2E,4S)- |
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| Synonym | More Synonyms |
| Description | Taltobulin intermediate-4 is an intermediate in the synthesis of Taltobulin (HY-15584). Taltobulin is a common toxin component in ADC preparation (ADC Cytotoxin), and it is also a powerful tubulin (Microtubule/Tubulin) inhibitor. Taltobulin disrupts tubulin polymerization, induces mitotic arrest, and induces apoptosis[1]. |
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| Related Catalog | |
| References |
| Density | 1.0±0.1 g/cm3 |
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| Boiling Point | 511.2±45.0 °C at 760 mmHg |
| Molecular Formula | C22H40N2O5 |
| Molecular Weight | 412.56 |
| Flash Point | 263.0±28.7 °C |
| Exact Mass | 412.293732 |
| LogP | 5.08 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.476 |
| MFCD29472352 |
| 2-Hexenoic acid, 4-[[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-3,3-dimethyl-1-oxobutyl]methylamino]-2,5-dimethyl-, ethyl ester, (2E,4S)- |
| Ethyl (2E,4S)-2,5-dimethyl-4-[methyl(3-methyl-N-{[(2-methyl-2-propanyl)oxy]carbonyl}-L-valyl)amino]-2-hexenoate |