SirReal1-O-propargyl

Modify Date: 2025-09-09 15:10:33

SirReal1-O-propargyl structure	Common Name	SirReal1-O-propargyl
	CAS Number	1862237-99-7	Molecular Weight	424.54
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₂₀N₄O₂S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of SirReal1-O-propargyl

PROTAC Sirt2-binding moiety 1 is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. For the development of sirtuin rearranging ligands (SirReals)-based PROTAC[1].

Name	PROTAC Sirt2-binding moiety 1

Description	PROTAC Sirt2-binding moiety 1 is a selective and highly potent Sirtuin 2 (Sirt2) inhibitor, with an IC50 of 2.4 μM. For the development of sirtuin rearranging ligands (SirReals)-based PROTAC[1].
Related Catalog	Research Areas >> Others
Target	IC50: 2.4 μM (Sirt2)[1].
References	[1]. Schiedel M, et al. Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals). J Med Chem. 2018 Jan 25;61(2):482-491.

Molecular Formula	C₂₁H₂₀N₄O₂S₂
Molecular Weight	424.54
Storage condition	2-8℃

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: SirReal1-O-propargyl
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Purity: 98.0%
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The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.