(+)-Dihydrocalanolide A

Modify Date: 2025-09-26 12:10:51

(+)-Dihydrocalanolide A Structure
(+)-Dihydrocalanolide A structure
Common Name (+)-Dihydrocalanolide A
CAS Number 183904-53-2 Molecular Weight 372.45500
Density 1.162g/cm3 Boiling Point 509ºC at 760mmHg
Molecular Formula C22H28O5 Melting Point N/A
MSDS N/A Flash Point 173.8ºC

 Use of (+)-Dihydrocalanolide A


(+)-Dihydrocalanolide A (DHCal A; NSC 678323) is an orally active nonnucleoside inhibitor of Reverse Transcriptase. (+)-Dihydrocalanolide A can be used to HIV infection research[1].

 Names

Name (+)-Dihydrocalanolide A
Synonym More Synonyms

 (+)-Dihydrocalanolide A Biological Activity

Description (+)-Dihydrocalanolide A (DHCal A; NSC 678323) is an orally active nonnucleoside inhibitor of Reverse Transcriptase. (+)-Dihydrocalanolide A can be used to HIV infection research[1].
Related Catalog
In Vivo (+)-Dihydrocalanolide A (25 mg/kg; p.o.; single dose) 具有良好的药代动力学参数,在 CD2F1 小鼠中的口服生物利用度为 64%[1]。
References

[1]. Newman RA, et al. Pharmaceutical properties of related calanolide compounds with activity against human immunodeficiency virus. J Pharm Sci. 1998 Sep;87(9):1077-80.  

 Chemical & Physical Properties

Density 1.162g/cm3
Boiling Point 509ºC at 760mmHg
Molecular Formula C22H28O5
Molecular Weight 372.45500
Flash Point 173.8ºC
Exact Mass 372.19400
PSA 68.90000
LogP 4.29950
Vapour Pressure 3.5E-11mmHg at 25°C
Index of Refraction 1.547

 Synonyms

Dihydrocalanolide A
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