AY77

Modify Date: 2024-01-20 17:57:28

AY77 structure	Common Name	AY77
	CAS Number	1835734-92-3	Molecular Weight	404.50
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₂₁H₃₂N₄O₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of AY77

AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of β-arrestin-2, respectively. AY77 potently induces intracellular Ca2+ release[1][2].

Name	AY77

Description	AY77 is a calcium-biased PAR2 agonist. AY77 shows an EC50 of 0.17 and 2 nM in PAR2-mediated the activation in the Gq pathway and recruitment of β-arrestin-2, respectively. AY77 potently induces intracellular Ca2+ release[1][2].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> GPCR/G Protein >> Protease-Activated Receptor (PAR) Research Areas >> Inflammation/Immunology
Target	PAR2[1]
References	[1]. Klösel I, et al. Discovery of Novel Nonpeptidic PAR2 Ligands. ACS Med Chem Lett. 2020 May 22;11(6):1316-1323. [2]. Jiang Y, et al. Biased Signaling by Agonists of Protease Activated Receptor 2. ACS Chem Biol. 2017 May 19;12(5):1217-1226.

Molecular Formula	C₂₁H₃₂N₄O₄
Molecular Weight	404.50

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: AY77
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Purity: 99.7%
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Contact: Yang
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AY77

Use of AY77

Names

AY77 Biological Activity

Chemical & Physical Properties

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.