Exatecan Intermediate 7

Modify Date: 2025-08-27 11:43:12

Exatecan Intermediate 7 structure	Common Name	Exatecan Intermediate 7
	CAS Number	182182-32-7	Molecular Weight	264.25
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₁₃H₁₃FN₂O₃	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Exatecan Intermediate 7

Exatecan Intermediate 7 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 7 can be used to synthesize Antibody-Drug Conjugates (ADCs).

Name	Exatecan Intermediate 7

Description	Exatecan Intermediate 7 is the intermediate of Exatecan (HY-13631) And Exatecan (DX-8951) is a DNA topoisomerase I inhibitor with an IC50 value of 2.2 μM (0.975 μg/mL) that can be used in cancer research. Exatecan Intermediate 7 can be used to synthesize Antibody-Drug Conjugates (ADCs).
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase
References	[1]. Kamihara, et al. Aminotetralone derivatives and process for producing the same. World Intellectual Property Organization, WO9626181 A1 1996-08-29. [2]. Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.

Description

Related Catalog

Signaling Pathways >> Cell Cycle/DNA Damage >> Topoisomerase

References

[1]. Kamihara, et al. Aminotetralone derivatives and process for producing the same. World Intellectual Property Organization, WO9626181 A1 1996-08-29.

[2]. Mitsui I, et al. A new water-soluble camptothecin derivative, DX-8951f, exhibits potent antitumor activity against human tumors in vitro and in vivo. Jpn J Cancer Res. 1995 Aug;86(8):776-82.