LYS228
Modify Date: 2025-08-25 15:48:11
LYS228 structure
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Common Name | LYS228 | ||
|---|---|---|---|---|
| CAS Number | 1810051-96-7 | Molecular Weight | 518.478 | |
| Density | 2.1±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C16H18N6O10S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of LYS228LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml; LYS228 is stable against Metallo-β-lactamases (MBLs), and shows small or no MIC shifts for most SBLs (serine β-lactamases), including CTX-Ms, KPCs and OXA-types. Bacterial Infection Phase 2 Clinical |
| Name | 29H7N9ξ1B |
|---|---|
| Synonym | More Synonyms |
| Description | LYS228 is a novel potent monobactam that shows potent activity against carbapenem-resistant isolates of Enterobacteriaceae with MIC90 of 2 ug/ml; LYS228 is stable against Metallo-β-lactamases (MBLs), and shows small or no MIC shifts for most SBLs (serine β-lactamases), including CTX-Ms, KPCs and OXA-types. Bacterial Infection Phase 2 Clinical |
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| References | References 1. Reck F, et al. Bioorg Med Chem Lett. 2018 Feb 15;28(4):748-755. View Related Products by Target Bacterial Bacterial Infection |
| Density | 2.1±0.1 g/cm3 |
|---|---|
| Molecular Formula | C16H18N6O10S2 |
| Molecular Weight | 518.478 |
| Exact Mass | 518.052551 |
| LogP | -2.12 |
| Index of Refraction | 1.867 |
| 1-({(Z)-[1-(2-Amino-1,3-thiazol-4-yl)-2-oxo-2-({(3S,4R)-2-oxo-4-[(2-oxo-1,3-oxazolidin-3-yl)methyl]-1-sulfo-3-azetidinyl}amino)ethylidene]amino}oxy)cyclopropanecarboxylic acid |
| 29H7N9ξ1B |
| Cyclopropanecarboxylic acid, 1-[[[(1Z)-1-(2-amino-4-thiazolyl)-2-oxo-2-[[(3S,4R)-2-oxo-4-[(2-oxo-3-oxazolidinyl)methyl]-1-sulfo-3-azetidinyl]amino]ethylidene]amino]oxy]- |