MM-206

Modify Date: 2024-01-13 06:59:28

MM-206 Structure
MM-206 structure
 Common Name MM-206
CAS Number 1809581-87-0 Molecular Weight 497.458
Density 1.6±0.1 g/cm3 Boiling Point 601.9±65.0 °C at 760 mmHg
Molecular Formula C22H12F5NO3S2 Melting Point N/A
MSDS N/A Flash Point 317.8±34.3 °C

 Use of MM-206


A novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM, binds to the STAT3 coiled-coil domain (CCD); also inhibits G-CSF-induced STAT3 phosphorylation in AML cell lines with IC50 of 0.8-1.9 uM,

 Names

Name MM 206
Synonym More Synonyms

 MM-206 Biological Activity

Description A novel small molecule STAT3 inhibitor that inhibits STAT3 DNA binding activity with IC50 of 1.16 uM, binds to the STAT3 coiled-coil domain (CCD); also inhibits G-CSF-induced STAT3 phosphorylation in AML cell lines with IC50 of 0.8-1.9 uM,
References References 1. Minus MB, et al. Angew Chem Int Ed Engl. 2015 Oct 26;54(44):13085-9. View Related Products by Target STAT

 Chemical & Physical Properties

Density 1.6±0.1 g/cm3
Boiling Point 601.9±65.0 °C at 760 mmHg
Molecular Formula C22H12F5NO3S2
Molecular Weight 497.458
Flash Point 317.8±34.3 °C
Exact Mass 497.017883
LogP 5.81
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.694

 Synonyms

MFCD30179936
Benzenesulfonamide, 2,3,4,5,6-pentafluoro-N-[4-hydroxy-3-(phenylthio)-1-naphthalenyl]-
2,3,4,5,6-Pentafluoro-N-(4-hydroxy-3-(phenylthio)naphthalen-1-yl)benzenesulfonamide
2,3,4,5,6-Pentafluoro-N-[4-hydroxy-3-(phenylsulfanyl)-1-naphthyl]benzenesulfonamide
MM 206
MM-206
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Chemsrc provides MM-206(CAS#:1809581-87-0) MSDS, density, melting point, boiling point, structure, formula, molecular weight etc. Articles of MM-206 are included as well.>> amp version: MM-206

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